Package: loki-doc (2.4.7.4-7)

MCMC linkage analysis on general pedigrees (PS manual)

Performs Markov chain Monte Carlo multipoint linkage analysis on large, complex pedigrees. The current package supports analyses on quantitative traits only, although this restriction will be lifted in later versions. Joint estimation of QTL number, position and effects uses Reversible Jump MCMC. It is also possible to perform affected only IBD sharing analyses.

Documentation on how to use Simon Heath's "prep" and "loki" tools for MCMC genetic linkage and IBD analysis on general pedigrees.