Pakket: ruby-crb-blast (0.6.9-1)
Verwijzigingen voor ruby-crb-blast
Trisquel bronnen:
Het bronpakket ruby-crb-blast downloaden:
- [ruby-crb-blast_0.6.9-1.dsc]
- [ruby-crb-blast_0.6.9.orig.tar.gz]
- [ruby-crb-blast_0.6.9-1.debian.tar.xz]
Beheerder:
Original Maintainers:
- Debian Ruby Extras Maintainers (Mailarchief)
- Michael R. Crusoe
Externe bronnen:
- Homepage [github.com]
Vergelijkbare pakketten:
Run conditional reciprocal best blast
CRB-BLAST is a novel method for finding orthologs between one set of sequences and another. This is particularly useful in genome and transcriptome annotation.
CRB-BLAST initially performs a standard reciprocal best BLAST. It does this by performing BLAST alignments of query->target and target->query. Reciprocal best BLAST hits are those where the best match for any given query sequence in the query->target alignment is also the best hit of the match in the reverse (target->query) alignment.
Reciprocal best BLAST is a very conservative way to assign orthologs. The main innovation in CRB-BLAST is to learn an appropriate e-value cutoff to apply to each pairwise alignment by taking into account the overall relatedness of the two datasets being compared. This is done by fitting a function to the distribution of alignment e-values over sequence lengths. The function provides the e-value cutoff for a sequence of given length.
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