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Balík: rna-star (2.5.4b+dfsg-1)

ultrafast universal RNA-seq aligner

Spliced Transcripts Alignment to a Reference (STAR) software based on a previously undescribed RNA-seq alignment algorithm that uses sequential maximum mappable seed search in uncompressed suffix arrays followed by seed clustering and stitching procedure. STAR outperforms other aligners by a factor of >50 in mapping speed, aligning to the human genome 550 million 2 × 76 bp paired-end reads per hour on a modest 12-core server, while at the same time improving alignment sensitivity and precision. In addition to unbiased de novo detection of canonical junctions, STAR can discover non-canonical splices and chimeric (fusion) transcripts, and is also capable of mapping full-length RNA sequences. Using Roche 454 sequencing of reverse transcription polymerase chain reaction amplicons, the authors experimentally validated 1960 novel intergenic splice junctions with an 80-90% success rate, corroborating the high precision of the STAR mapping strategy.

Ostatné balíky súvisiace s balíkom rna-star

  • závisí
  • odporúča
  • navrhuje
  • dep: libc6 (>= 2.14)
    GNU C Library: Shared libraries
    tiež virtuálny balík poskytovaný balíkom libc6-udeb
  • dep: libgcc1 (>= 1:3.3.1)
    GCC support library
  • dep: libgomp1 (>= 4.9)
    GCC OpenMP (GOMP) support library
  • dep: libhts2 (>= 1.0)
    C library for high-throughput sequencing data formats
  • dep: libstdc++6 (>= 5.2)
    GNU Standard C++ Library v3

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amd64 370.8 kB855 kB [zoznam súborov]