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[ 原始碼: conservation-code  ]

套件: conservation-code (20110309.0-8)

conservation-code 的相關超連結

conservation-code

Trisquel 的資源:

下載原始碼套件 conservation-code

維護者:

Original Maintainers:

  • Debian Med Packaging Team (郵件存檔)
  • Laszlo Kajan
  • Andreas Tille

外部的資源:

  • 主頁 [compbio.cs.princeton.edu]

相似套件:

protein sequence conservation scoring tool

This package provides score_conservation(1), a tool to score protein sequence conservation.

The following conservation scoring methods are implemented:

 * sum of pairs
 * weighted sum of pairs
 * Shannon entropy
 * Shannon entropy with property groupings (Mirny and Shakhnovich 1995,
   Valdar and Thornton 2001)
 * relative entropy with property groupings (Williamson 1995)
 * von Neumann entropy (Caffrey et al 2004)
 * relative entropy (Samudrala and Wang 2006)
 * Jensen-Shannon divergence (Capra and Singh 2007)

A window-based extension that incorporates the estimated conservation of sequentially adjacent residues into the score for each column is also given. This window approach can be applied to any of the conservation scoring methods.

The program accepts alignments in the CLUSTAL and FASTA formats.

The sequence-specific output can be used as the conservation input for concavity.

Conservation is highly predictive in identifying catalytic sites and residues near bound ligands.

其他與 conservation-code 有關的套件

  • 依賴
  • 推薦
  • 建議
  • dep: python3
    interactive high-level object-oriented language (default python3 version)
  • dep: python3-numpy
    Fast array facility to the Python 3 language
  • enh: concavity
    predictor of protein ligand binding sites from structure and conservation

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