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[ 源代码: hisat2  ]

软件包: hisat2 (2.1.0-1)

graph-based alignment of short nucleotide reads to many genomes

HISAT2 is a fast and sensitive alignment program for mapping next-generation sequencing reads (both DNA and RNA) to a population of human genomes (as well as against a single reference genome). Based on an extension of BWT for graphs a graph FM index (GFM) was designed and implementd. In addition to using one global GFM index that represents a population of human genomes, HISAT2 uses a large set of small GFM indexes that collectively cover the whole genome (each index representing a genomic region of 56 Kbp, with 55,000 indexes needed to cover the human population). These small indexes (called local indexes), combined with several alignment strategies, enable rapid and accurate alignment of sequencing reads. This new indexing scheme is called a Hierarchical Graph FM index (HGFM).

其他与 hisat2 有关的软件包

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  • 推荐
  • 建议
  • dep: libc6 (>= 2.14)
    GNU C Library: Shared libraries
    同时作为一个虚包由这些包填实: libc6-udeb
  • dep: libgcc1 (>= 1:3.0)
    GCC support library
  • dep: libstdc++6 (>= 5.2)
    GNU Standard C++ Library v3
  • dep: perl
    Larry Wall's Practical Extraction and Report Language
  • dep: python
    interactive high-level object-oriented language (default version)

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amd64 1,248.0 kB5023 kB [文件列表]